Tympanic Exostoses

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Severe Multiple Cartilaginous Exostoses

Multiple cartilaginous exostoses (MCE) is one of the most common inherited skeletal disorders. A collection of 1124 cases was reported by Stock and Barrington (1925). Recently other large series have been published by Solomon (1963) and Sauer (1979). Different terms have been used for it such as multiple exostoses, hereditary multiple exostoses and diaphyseal aclasis. The swelling or "lump" are...

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Hereditary multiple exostoses.

Hereditary multiple exostoses (HME) is a skeletal disorder which primarily affects enchondral bone during growth. It is characterised by multiple exostoses, usually arising in the juxtaepiphyseal region of the long bones. Exostoses that affect "almost every bone in the body" were first mentioned by John Hunter in his Lectures on the principles of surgery in 1786.1 The first family affected by H...

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Manifestations of hereditary multiple exostoses.

The solitary osteochondroma, a common pediatric bone tumor, is a cartilage-capped exostosis. Hereditary multiple exostosis is an autosomal dominant disorder manifested by the presence of multiple osteochondromas. Linkage analysis has implicated mutations in the EXT gene family, resulting in an error in the regulation of normal chondrocyte proliferation and maturation that leads to abnormal bone...

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Exostoses of the external auditory canal.

An incidental post-mortem finding is reported. Its clinical relevance is discussed. It is suggested that some EAC exostoses may have a similar origin and thus an association with IAC exostoses.

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Tympanic paraganglioma: two cases.

Paragangliomas originate from glomus bodies which are non-working temporal bone chemoreceptors, derived from neuroectodermal cells of the neural crest. Tympanic paragangliomas have pulsatile tinnitus as its most frequent symptom, followed by conductive hearing loss, otalgia and ear fullness. Some patients may present vertigo and otorhagia. Our goal is to present two cases of tympanic paragangli...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1921

ISSN: 0035-9157

DOI: 10.1177/003591572101401209